Intrinsic factor meaning

The intrinsic factor is a protein secreted by the stomach that is essential for the absorption of vitamin B12 in the small intestine.


Intrinsic factor definitions

Word backwards cisnirtni rotcaf
Part of speech The term "intrinsic factor" is a noun.
Syllabic division in-trin-sic fac-tor
Plural The plural of the word intrinsic factor is intrinsic factors.
Total letters 15
Vogais (3) i,a,o
Consonants (6) n,t,r,s,c,f

Intrinsic factor is a glycoprotein produced by the parietal cells of the stomach. This protein is essential for the absorption of vitamin B12 in the small intestine. Without intrinsic factor, vitamin B12 cannot be absorbed and utilized by the body, leading to a deficiency.

Vitamin B12 is crucial for various bodily functions, including the formation of red blood cells, neurological function, and DNA synthesis. A deficiency in vitamin B12 can lead to symptoms such as fatigue, weakness, neurological issues, and anemia.

Function of Intrinsic Factor

Intrinsic factor binds to vitamin B12 in the stomach, forming a complex that is then absorbed in the ileum, the last part of the small intestine. This absorption process is crucial for maintaining adequate levels of vitamin B12 in the body.

Intrinsic Factor Deficiency

Individuals with an intrinsic factor deficiency are unable to absorb vitamin B12 efficiently, even if they consume adequate amounts of the vitamin in their diet. This condition can lead to pernicious anemia, a type of anemia caused by vitamin B12 deficiency.

Treatment of Intrinsic Factor Deficiency

Individuals with an intrinsic factor deficiency are often treated with vitamin B12 injections to bypass the need for intrinsic factor in the absorption process. These injections provide the body with the necessary vitamin B12 directly, bypassing the need for intrinsic factor.

In conclusion, intrinsic factor plays a crucial role in the absorption of vitamin B12 in the body. Without intrinsic factor, vitamin B12 deficiency can occur, leading to various health issues. Understanding the importance of intrinsic factor highlights the significance of proper vitamin B12 absorption for overall health and well-being.


Intrinsic factor Examples

  1. The role of intrinsic factor is essential for the absorption of vitamin B12 in the body.
  2. Intrinsic factor is produced by the parietal cells in the stomach lining.
  3. Individuals with pernicious anemia lack intrinsic factor, leading to vitamin B12 deficiency.
  4. The binding of vitamin B12 to intrinsic factor occurs in the small intestine.
  5. Intrinsic factor enables the transport of vitamin B12 across the intestinal lining into the bloodstream.
  6. Factors such as gastric bypass surgery can affect the production of intrinsic factor.
  7. Intrinsic factor plays a crucial role in preventing vitamin B12 deficiency.
  8. Intrinsic factor is necessary for the activation of certain enzymes in the body.
  9. A lack of intrinsic factor can result in neurological complications due to vitamin B12 deficiency.
  10. Intrinsic factor is a key protein involved in the absorption of vitamin B12 from food sources.


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  • Updated 27/04/2024 - 14:43:57