Presynaptic meaning

Presynaptic refers to the part of a neuron that releases neurotransmitters before the synaptic cleft.


Presynaptic definitions

Word backwards citpanyserp
Part of speech adjective
Syllabic division pre-sy-nap-tic
Plural The plural of presynaptic is presynaptics.
Total letters 11
Vogais (3) e,a,i
Consonants (7) p,r,s,y,n,t,c

Understanding Presynaptic Function

Presynaptic refers to a component of a biological synapse that is involved in transmitting signals from the neuron to the synaptic cleft. This process is crucial for communication between neurons and the overall function of the nervous system.

Key Features of Presynaptic Terminals

The presynaptic terminal contains synaptic vesicles that store neurotransmitters, which are chemical messengers responsible for signal transmission. When an action potential reaches the presynaptic terminal, it triggers the release of neurotransmitters into the synaptic cleft.

Neurotransmitter Release Mechanism

The release of neurotransmitters from the presynaptic terminal is a highly regulated process. When the action potential reaches the terminal, voltage-gated calcium channels open, allowing calcium ions to enter the terminal. This influx of calcium triggers the fusion of synaptic vesicles with the presynaptic membrane, releasing neurotransmitters into the synaptic cleft.

Role in Synaptic Transmission

The presynaptic terminal plays a crucial role in synaptic transmission, as it is responsible for initiating the communication between neurons. By releasing neurotransmitters into the synaptic cleft, the presynaptic terminal allows for the propagation of signals from one neuron to another.

Implications for Neurological Disorders

Disruptions in presynaptic function can lead to various neurological disorders, such as epilepsy, Parkinson's disease, and Alzheimer's disease. Understanding the mechanisms underlying presynaptic function is therefore essential for developing treatments for these disorders.

Future Research Directions

Ongoing research aims to further elucidate the complex processes involved in presynaptic function. By gaining a deeper understanding of how neurotransmitter release is regulated at the presynaptic terminal, scientists hope to uncover new therapeutic targets for neurological disorders.


Presynaptic Examples

  1. The release of neurotransmitters from the presynaptic neuron is essential for synaptic communication.
  2. Presynaptic inhibition can modulate the amount of neurotransmitters released at a synapse.
  3. Certain drugs can target presynaptic receptors to alter neuronal signaling.
  4. Presynaptic terminals contain vesicles filled with neurotransmitters ready for release.
  5. Presynaptic plasticity plays a role in synaptic strength and neural network dynamics.
  6. Presynaptic depolarization can trigger the release of neurotransmitters into the synaptic cleft.
  7. There are several mechanisms by which presynaptic neurons can regulate synaptic transmission.
  8. Presynaptic autoreceptors can provide feedback to regulate neurotransmitter release.
  9. The presynaptic neuron can communicate with the postsynaptic neuron through chemical signals.
  10. Presynaptic activity can be influenced by various factors such as calcium levels and second messenger systems.


Most accessed

Search the alphabet

  • #
  • Aa
  • Bb
  • Cc
  • Dd
  • Ee
  • Ff
  • Gg
  • Hh
  • Ii
  • Jj
  • Kk
  • Ll
  • Mm
  • Nn
  • Oo
  • Pp
  • Qq
  • Rr
  • Ss
  • Tt
  • Uu
  • Vv
  • Ww
  • Xx
  • Yy
  • Zz
  • Updated 18/06/2024 - 11:36:14