Phosphorylate meaning

Phosphorylate means to add a phosphate group to a molecule.


Phosphorylate definitions

Word backwards etalyrohpsohp
Part of speech The part of speech of the word "phosphorylate" is a verb.
Syllabic division phos-pho-ry-late
Plural The plural of phosphorylate is phosphorylates.
Total letters 13
Vogais (3) o,a,e
Consonants (7) p,h,s,r,y,l,t

Phosphorylation is a crucial biochemical process in living organisms, where a phosphate group is added to a molecule. This process plays a significant role in cellular signaling, energy storage, and various metabolic pathways.

Importance of Phosphorylation

Phosphorylation is essential for the activation or deactivation of proteins, enzymes, and other molecules in the body. It regulates important cellular functions, such as cell growth, division, and communication.

Mechanism of Phosphorylation

Phosphorylation occurs when a phosphate group is transferred from ATP (adenosine triphosphate) to a target molecule by specific enzymes called kinases. This process alters the structure and function of the target molecule, leading to various biological effects.

Role in Signal Transduction

Phosphorylation is a key mechanism in signal transduction pathways, where extracellular signals are transmitted into the cell to elicit a response. It allows cells to respond to changes in their environment and coordinate appropriate cellular activities.

Protein kinases, enzymes that catalyze phosphorylation reactions, are crucial components of signal transduction cascades. They phosphorylate specific target proteins, triggering a series of events that ultimately lead to a cellular response.

Phosphorylation in Disease

Aberrant phosphorylation is associated with various diseases, including cancer, diabetes, and neurodegenerative disorders. Dysregulation of protein phosphorylation can disrupt normal cellular processes and contribute to the development of these conditions.

Pharmacological Target

Given its significance in disease processes, phosphorylation has become a target for drug development. Pharmacological agents that modulate protein phosphorylation are being investigated as potential treatments for a range of diseases.

In conclusion, phosphorylation is a fundamental biochemical process with diverse roles in cellular function and disease. Understanding the mechanisms and regulation of phosphorylation is essential for advancing our knowledge of biology and developing new therapeutic interventions.


Phosphorylate Examples

  1. Phosphorylate your target protein to study its function in the cell.
  2. Researchers often phosphorylate specific amino acid residues to regulate protein activity.
  3. The enzyme kinase can phosphorylate other enzymes in a signaling pathway.
  4. Phosphorylate the substrate to initiate the biochemical reaction.
  5. The addition of a phosphate group can phosphorylate a molecule to change its properties.
  6. Phosphorylate the protein complex to enhance its stability.
  7. Cells often phosphorylate proteins as a response to external stimuli.
  8. Phosphorylate the receptor to modulate its signaling activity.
  9. Phosphorylate the transcription factor to regulate gene expression.
  10. Scientists use specific techniques to phosphorylate proteins in the laboratory.


Most accessed

Search the alphabet

  • #
  • Aa
  • Bb
  • Cc
  • Dd
  • Ee
  • Ff
  • Gg
  • Hh
  • Ii
  • Jj
  • Kk
  • Ll
  • Mm
  • Nn
  • Oo
  • Pp
  • Qq
  • Rr
  • Ss
  • Tt
  • Uu
  • Vv
  • Ww
  • Xx
  • Yy
  • Zz
  • Updated 02/05/2024 - 13:43:55