Immunohistochemistry meaning

Immunohistochemistry is a technique used to visualize specific antigens in tissues by utilizing antibodies conjugated with fluorescent dyes or enzymes.


Immunohistochemistry definitions

Word backwards yrtsimehcotsihonummi
Part of speech The part of speech of the word "immunohistochemistry" is a noun.
Syllabic division The syllable separation of the word immunohistochemistry is im-mu-no-his-to-chem-is-try.
Plural The plural form of the word "immunohistochemistry" is "immunohistochemistries."
Total letters 20
Vogais (4) i,u,o,e
Consonants (8) m,n,h,s,t,c,r,y

Immunohistochemistry is a powerful technique used in the field of pathology to detect the presence, abundance, and localization of specific proteins in cells and tissues. This technique combines the principles of immunology and histology to visualize the distribution of target antigens in biological samples.

Principles of Immunohistochemistry

Immunohistochemistry relies on the specific binding of primary antibodies to target antigens present in the tissue sample. Once the primary antibody binds to the antigen, a secondary antibody linked to a detection system is used to visualize the antigen-antibody complex. Common detection systems include enzymes, fluorophores, or colloidal gold particles.

Applications of Immunohistochemistry

Immunohistochemistry has a wide range of applications in research and clinical settings. It is commonly used to diagnose various types of cancer by detecting specific markers associated with different tumor types. Additionally, immunohistochemistry can be used to study the expression of proteins in normal tissues, investigate disease mechanisms, and evaluate the effectiveness of drug treatments.

Advantages of Immunohistochemistry

One of the main advantages of immunohistochemistry is its ability to provide spatial information about protein expression in tissues. This technique allows researchers and pathologists to identify the subcellular localization of proteins within different cell types. Immunohistochemistry also provides quantitative data, making it a valuable tool for comparing protein levels between different samples.

Overall, immunohistochemistry plays a crucial role in advancing our understanding of disease biology and pathology. By allowing researchers to visualize and quantify protein expression in tissues, this technique has become an indispensable tool in molecular biology and medical diagnostics.


Immunohistochemistry Examples

  1. The researcher used immunohistochemistry to study the expression of a specific protein in cancer cells.
  2. Immunohistochemistry showed a high level of inflammation in the tissue sample.
  3. The pathologist utilized immunohistochemistry to help diagnose the type of tumor present.
  4. The immunohistochemistry results indicated a potential immune response in the infected area.
  5. Immunohistochemistry staining revealed the presence of abnormal cells in the biopsy.
  6. Researchers used immunohistochemistry to visualize the distribution of neurotransmitters in the brain.
  7. Immunohistochemistry analysis confirmed the effectiveness of the new drug in targeting cancer cells.
  8. The immunohistochemistry technique helped differentiate between different types of cells in the sample.
  9. Immunohistochemistry testing demonstrated the progression of a disease in the tissue sample.
  10. The immunohistochemistry assay provided insights into the mechanism of action of the experimental treatment.


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  • Updated 31/03/2024 - 08:42:27