Immortalization meaning

Immortalization refers to the process of enabling cells or organisms to live indefinitely, often achieved by altering their cellular mechanisms to prevent death.


Immortalization definitions

Word backwards noitazilatrommi
Part of speech The word "immortalization" is a noun. It refers to the act of making someone or something immortal or enduring forever.
Syllabic division The syllable separation of the word "immortalization" is: im-mor-tal-i-za-tion.
Plural The plural of "immortalization" is "immortalizations."
Total letters 15
Vogais (3) i,o,a
Consonants (6) m,r,t,l,z,n

The Concept of Immortalization

Immortalization refers to the process by which cells acquire the ability to proliferate indefinitely. This phenomenon is often observed in cancer cells, which can divide endlessly and evade the usual mechanisms of cellular aging and death. Immortalized cells do not undergo senescence, a state in which normal cells no longer divide, leading them to play a crucial role in scientific research.

Mechanisms of Cell Immortalization

There are several mechanisms that facilitate the process of immortalization. One prominent mechanism involves the activation of telomerase, an enzyme that extends the telomeres at the ends of chromosomes. In normal somatic cells, telomeres shorten with each cell division, eventually leading to cell death. However, immortalized cells often activate telomerase, allowing them to maintain their telomere length and survive indefinitely.

Types of Immortalized Cells

Researchers typically utilize various types of immortalized cells in their studies. Common examples include HeLa cells, derived from cervical cancer, and HEK293 cells, derived from human embryonic kidney cells. These cell lines are essential for biological research, drug development, and vaccine production due to their stable growth and reproducibility.

Applications of Immortalization in Research

Immortalized cells are crucial to many fields of research. They are used in cancer research to better understand the mechanisms of tumor growth and progression. Additionally, they serve as vital tools in drug discovery, allowing researchers to screen potential therapeutic agents efficiently. Furthermore, immortalized cells contribute to developing vaccines and studying various diseases, as they can be manipulated to express specific genes or proteins.

Ethical Considerations in Immortalization

The process of immortalization raises important ethical questions, particularly concerning the origins of the cells used. Many immortalized cell lines were derived from human tissues without consent, leading to ongoing discussions about the rights of donors and the ethical implications of using these cells in research. Proper guidelines and regulations are necessary to ensure ethical practices while advancing scientific knowledge.

Future of Immortalization in Science

The future of immortalization in scientific research looks promising. Advances in genetic engineering and biotechnology may pave the way for creating more ethically sourced immortalized cell lines. Additionally, new techniques such as induced pluripotent stem cells (iPSCs) could provide alternative platforms for research without the ethical dilemmas associated with traditional immortalization methods. As science progresses, understanding immortalization and its implications will continue to evolve, shaping the landscape of biomedical research.


Immortalization Examples

  1. The artist's latest sculpture serves as an immortalization of cultural heritage through modern design.
  2. The novel provides an immortalization of the protagonist's struggles, ensuring that their story is never forgotten.
  3. The film's impact on society led to the immortalization of its lead actor in the hearts of fans worldwide.
  4. The monument stands as an immortalization of the sacrifices made by soldiers during the war.
  5. Through the act of writing, she aimed for the immortalization of her family's history.
  6. The digital archive functions as an immortalization of ancient texts that would otherwise be lost to time.
  7. Their friendship was captured in numerous photographs, resulting in the immortalization of their bond.
  8. The song became a classic, leading to the immortalization of its lyrics in music history.
  9. The conference aimed at discussing the immortalization of indigenous languages in modern education.
  10. His groundbreaking research led to the immortalization of his theories in academic circles.


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  • Updated 24/07/2024 - 21:33:21