Benzylic definitions
| Word backwards | cilyzneb |
|---|---|
| Part of speech | The word "benzylic" is an adjective. It is used to describe compounds or groups that are attached to a benzene ring. |
| Syllabic division | ben-zy-lic |
| Plural | The plural of benzylic is benzylics. |
| Total letters | 8 |
| Vogais (2) | e,i |
| Consonants (6) | b,n,z,y,l,c |
In organic chemistry, a benzylic compound refers to a molecule that has a phenyl group attached to a sp3 hybridized carbon atom next to an aromatic ring. This carbon atom is known as a benzylic carbon, and compounds with this structural feature are called benzylic compounds.
Structure and Properties
The presence of a benzylic group can significantly impact the reactivity and stability of a molecule. Benzylic compounds are known to exhibit resonance stabilization due to the delocalization of electrons within the phenyl ring. This resonance effect makes benzylic carbon atoms less susceptible to nucleophilic attack compared to other alkyl carbon atoms.
Reactivity
Benzylic compounds are commonly used in organic synthesis due to their unique reactivity patterns. The benzylic carbon is often involved in various types of reactions, including oxidation, reduction, substitution, and elimination reactions. The presence of a benzylic group can influence the regioselectivity and stereoselectivity of these reactions.
Applications
Benzylic compounds are found in a wide range of natural and synthetic molecules, including pharmaceuticals, agrochemicals, and fragrances. The benzylic position is often considered a valuable site for introducing functional groups or modifying the properties of the parent molecule. This strategic placement can enhance the biological activity or physical properties of the compound.
Overall, benzylic compounds play a crucial role in organic chemistry and drug discovery due to their distinct reactivity and structural features. Understanding the behavior of benzylic groups can provide valuable insights for designing novel molecules with desired properties.
Benzylic Examples
- The benzylic carbon in this molecule is highly reactive.
- The benzylic position plays a crucial role in the mechanism of this reaction.
- Substituents on the benzylic carbon can impact the stability of the compound.
- The benzylic hydrogen atoms are more acidic compared to other alkyl groups.
- The benzylic halide served as a good leaving group in the synthesis.
- The benzylic substituent enhances the electrophilicity of the neighboring carbon.
- The oxidation of a benzylic alcohol forms a benzylic ketone.
- The benzylic position is susceptible to oxidation under certain conditions.
- A benzylic rearrangement occurred during the isolation of the product.
- The benzylic group imparts aromatic character to the compound.