Cytochalasin meaning

Cytochalasin is a fungal-derived compound that inhibits actin polymerization by blocking the addition of monomers to the growing filament.


Cytochalasin definitions

Word backwards nisalahcotyc
Part of speech The word cytochalasin is a noun.
Syllabic division cy-to-cha-la-sin
Plural The plural of the word cytochalasin is cytochalasins.
Total letters 12
Vogais (3) o,a,i
Consonants (7) c,y,t,h,l,s,n

Cytochalasin is a natural compound that is known for its ability to disrupt actin polymerization, a crucial process in cell migration and division. This compound is derived from various species of fungi, particularly from the genus Helminthosporium. Cytochalasin works by binding to the fast-growing ends of actin filaments, preventing the addition of more monomers and ultimately causing the disassembly of the cytoskeleton.

One of the primary uses of cytochalasin in research is to study the mechanisms of cell motility and cytokinesis. By inhibiting actin polymerization, researchers can observe how cells respond when their cytoskeleton is disrupted. This can provide valuable insights into the essential role actin plays in cellular processes.

Effects on Cell Division

When cells are treated with cytochalasin, they are unable to undergo cytokinesis properly. This results in the formation of multinucleated cells, as the daughter cells are unable to separate completely. This phenomenon has been extensively studied to understand the underlying mechanisms of cell division and the role of actin in this process.

Impact on Cellular Migration

Actin polymerization is also crucial for cellular migration. By disrupting this process, cytochalasin can inhibit the movement of cells. This has implications for processes such as wound healing, immune response, and cancer metastasis, where cell migration plays a significant role.

Overall, cytochalasin is a valuable tool in cell biology research due to its specific mechanism of action on actin filaments. By studying the effects of this compound, scientists can gain a better understanding of fundamental cellular processes and potentially identify new targets for therapeutic interventions in various diseases.


Cytochalasin Examples

  1. Researchers use cytochalasin to study the role of actin filaments in cell motility.
  2. Cytochalasin is often used in experiments to disrupt the cytoskeleton of cells.
  3. Pharmacologists are investigating the potential medical applications of cytochalasin compounds.
  4. Cell biologists use cytochalasin to investigate cellular processes such as endocytosis.
  5. Cytochalasin treatment can affect the shape and movement of cells in culture.
  6. Scientists are studying the mechanisms of action of cytochalasin derivatives.
  7. Cytochalasin is known for its ability to inhibit cell division in certain organisms.
  8. Researchers are exploring the use of cytochalasin in cancer treatment strategies.
  9. Cytochalasin can interfere with the formation of contractile rings during cell division.
  10. The effects of cytochalasin on cell morphology are a subject of ongoing research.


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  • Updated 06/07/2024 - 12:44:13