Cross-resistance meaning

Cross-resistance refers to the ability of a microorganism to resist multiple antibiotics due to a shared mechanism of resistance.


Cross-resistance definitions

Word backwards ecnatsiser-ssorc
Part of speech noun
Syllabic division cross-re-sis-tance
Plural The plural of the word cross-resistance is cross-resistances.
Total letters 15
Vogais (4) o,e,i,a
Consonants (5) c,r,s,t,n

Cross-Resistance: Understanding the Phenomenon

Cross-resistance occurs when an organism develops resistance to one particular drug or treatment, which then leads to resistance to another drug with a similar mode of action. This phenomenon is a significant concern in various fields, including medicine, agriculture, and pest control. Understanding cross-resistance is crucial for developing effective strategies to combat drug resistance.

Mechanism of Cross-Resistance

The mechanism behind cross-resistance involves the shared pathways or mechanisms of action between drugs. When an organism develops resistance to one drug, it can also confer resistance to other drugs that target similar pathways. This shared resistance mechanism can significantly reduce the effectiveness of multiple treatments.

Implications in Medicine

Cross-resistance is a major issue in the field of medicine, particularly in the treatment of infectious diseases such as bacteria and viruses. If an organism develops resistance to one antibiotic, it may also become resistant to other antibiotics with similar mechanisms of action. This can limit treatment options and make infections more challenging to control.

Impact in Agriculture

In agriculture, cross-resistance poses a significant threat to the effectiveness of pesticides and herbicides. Pests and weeds can develop resistance to one chemical, leading to reduced efficacy of other chemicals within the same class. This can result in crop damage and lower yields for farmers.

Strategies to Address Cross-Resistance

To combat cross-resistance, researchers and practitioners must develop diverse treatment strategies that target different pathways or mechanisms of action. By rotating different treatments or using combination therapies, it is possible to reduce the risk of cross-resistance and prolong the effectiveness of treatments.

Adaptation and evolution play key roles in the development of cross-resistance, highlighting the importance of staying ahead of evolving threats. With a deeper understanding of the mechanisms behind cross-resistance, experts can work towards mitigating its impact and preserving the effectiveness of treatments for the future.


Cross-resistance Examples

  1. The development of resistance to antibiotics in bacteria can lead to cross-resistance to other drugs.
  2. Exposure to one pesticide may result in cross-resistance to similar chemicals in insects.
  3. Some cancer treatments can cause cross-resistance to other chemotherapy drugs.
  4. Overuse of herbicides can create cross-resistance in weeds, making them harder to control.
  5. Resistance to one antiviral medication can lead to cross-resistance to other antivirals.
  6. In agriculture, the use of certain fungicides can result in cross-resistance in fungal populations.
  7. People with allergies to certain antibiotics may experience cross-resistance to related drugs.
  8. The misuse of antibiotics in livestock can contribute to cross-resistance in human pathogens.
  9. Continued use of the same insecticide can cause cross-resistance in pest populations over time.
  10. Cross-resistance between different classes of insecticides is a growing concern in pest management.


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  • Updated 20/06/2024 - 22:00:50