Complement meaning

A complement is a word or group of words that completes the predicate in a sentence, providing additional information or completing the meaning.


Complement definitions

Word backwards tnemelpmoc
Part of speech Noun
Syllabic division com-ple-ment
Plural The plural of the word "complement" is "complements."
Total letters 10
Vogais (2) o,e
Consonants (6) c,m,p,l,n,t

Complement, in biology, refers to a group of proteins that work together to play a crucial role in the immune system. These proteins complement the action of antibodies in defending the body against pathogens such as bacteria and viruses. The complement system is a complex network of proteins that can be activated through three different pathways: the classical pathway, the lectin pathway, and the alternative pathway.

Function of Complement Proteins

Complement proteins function by enhancing the ability of antibodies and phagocytic cells to clear pathogens from the body. They can also directly attack the surface of pathogens, leading to their destruction. Additionally, complement proteins play a role in inflammation, immune regulation, and the clearance of immune complexes.

Activation of the Complement System

The complement system can be activated through various triggers, including the presence of antibodies bound to pathogens, foreign substances on the surface of pathogens, or spontaneous hydrolysis. Once activated, the complement proteins undergo a cascade of enzymatic reactions that lead to the formation of membrane attack complexes, which can create pores in the membranes of pathogens, causing their lysis.

Regulation of Complement Activation

While the complement system is essential for immune defense, overactivation can lead to tissue damage and inflammatory diseases. Therefore, the complement system is tightly regulated by proteins that prevent its excessive activation on host cells. Dysregulation of the complement system can result in autoimmune diseases and other immune-related disorders.

Complement proteins play a critical role in the immune response by enhancing the activity of antibodies and phagocytic cells. They contribute to the clearance of pathogens and the regulation of inflammation and immune complexes. It is important to understand the function and activation of the complement system for the development of therapies for immune-related disorders.


Complement Examples

  1. The red wine complemented the steak perfectly.
  2. She wore a necklace that was the perfect complement to her dress.
  3. His skills in marketing were a great complement to her expertise in sales.
  4. The professor stated that the two theories were complements rather than conflicting ideas.
  5. The bold curtains were the perfect complement to the neutral walls.
  6. The new software was introduced as a complement to the existing programs.
  7. The contrasting flavors of sweet and salty complemented each other in the dish.
  8. His calm demeanor was a complement to her high-energy personality.
  9. The accessories she wore complemented her outfit beautifully.
  10. The new law was designed to complement existing regulations.


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  • Updated 21/06/2024 - 08:33:53