Clofibrates meaning

Clofibrates are a class of lipid-lowering drugs that help reduce cholesterol levels in the blood.


Clofibrates definitions

Word backwards setarbifolc
Part of speech Noun
Syllabic division clo-fi-brates
Plural The plural of clofibrate is clofibrates.
Total letters 11
Vogais (4) o,i,a,e
Consonants (7) c,l,f,b,r,t,s

Clofibrates are a class of drugs known as fibrates, which are primarily used to lower high levels of cholesterol and triglycerides in the blood. They work by increasing the breakdown of fats in the body and reducing the production of triglycerides in the liver.

Mechanism of Action

Clofibrates work by activating a specific receptor known as PPAR-alpha, which regulates genes involved in lipid metabolism. By enhancing the activity of this receptor, clofibrates help to increase the breakdown of fatty acids and reduce the production of triglycerides in the liver. This leads to a decrease in the levels of both total cholesterol and triglycerides in the blood.

Uses

Clofibrates are prescribed to patients with high levels of cholesterol and triglycerides who have not responded adequately to lifestyle changes such as diet and exercise. They are often used in combination with other medications, such as statins, to further reduce the risk of cardiovascular disease.

Side Effects

Common side effects of clofibrates include gastrointestinal issues such as nausea, vomiting, and diarrhea. They can also cause liver problems, muscle pain, and an increased risk of bleeding. It is important to discuss any concerns about side effects with your healthcare provider.

In conclusion, clofibrates are a medication used to lower cholesterol and triglyceride levels in the blood. They work by activating a specific receptor that regulates lipid metabolism, leading to a decrease in fat production in the liver. While effective, they can also cause side effects that should be monitored closely by a healthcare professional.


Clofibrates Examples

  1. Clofibrates are commonly used as a treatment for high cholesterol.
  2. Patients with hyperlipidemia may be prescribed clofibrates by their doctor.
  3. Research has shown that clofibrates can help reduce the risk of cardiovascular disease.
  4. Some people experience side effects when taking clofibrates, such as muscle pain.
  5. Clofibrates work by increasing the breakdown of fats in the body.
  6. It is important to follow the prescribed dosage of clofibrates to avoid complications.
  7. Clofibrates are not suitable for everyone and should be used with caution in certain populations.
  8. Doctors may monitor liver function in patients taking clofibrates due to potential side effects.
  9. Clofibrates are just one option among many for managing high cholesterol levels.
  10. Before starting clofibrates, patients should discuss any existing medical conditions with their healthcare provider.


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  • Updated 02/07/2024 - 20:20:01