Biotransformations meaning

Biotransformations refer to the chemical modifications that occur in a substance within a living organism.


Biotransformations definitions

Word backwards snoitamrofsnartoib
Part of speech noun
Syllabic division bi-o-trans-for-ma-tions
Plural The plural of the word biotransformations is biotransformations.
Total letters 18
Vogais (3) i,o,a
Consonants (7) b,t,r,n,s,f,m

Biotransformations refer to the chemical modifications that occur in living organisms, transforming various compounds into different forms. These transformations are crucial for the metabolism of drugs, nutrients, and environmental pollutants.

Types of Biotransformations

There are two main types of biotransformations: Phase I and Phase II reactions. Phase I reactions involve processes like oxidation, reduction, and hydrolysis that introduce or expose functional groups on a compound. Phase II reactions, on the other hand, conjugate the compound with another molecule to increase its solubility for excretion.

Key Enzymes

Enzymes play a crucial role in catalyzing biotransformations. For example, cytochrome P450 enzymes are responsible for many Phase I reactions, while transferases and conjugating enzymes drive Phase II reactions. These enzymes are highly specific and essential for the proper functioning of biotransformation pathways.

Role in Drug Metabolism

Biotransformations are especially significant in drug metabolism. Many drugs are administered in an inactive form and require biotransformation to become active or to be eliminated from the body. Understanding the biotransformation pathways of drugs is essential for predicting their efficacy and potential side effects.

Overall, biotransformations are vital processes in living organisms that regulate the metabolism of various compounds. Research in this field not only deepens our understanding of biological systems but also has practical applications in drug development and environmental management.


Biotransformations Examples

  1. Biotransformations are crucial in the metabolism of drugs within the body.
  2. The bacteria in the soil play a key role in biotransformations of organic matter.
  3. Certain enzymes in the liver facilitate biotransformation of toxins into less harmful substances.
  4. Researchers are studying biotransformations in microorganisms to improve biofuel production.
  5. Bioremediation utilizes biotransformations to break down pollutants in the environment.
  6. Understanding biotransformations can aid in the development of new pharmaceuticals.
  7. Genetically modified organisms are used in biotransformations for various industrial processes.
  8. Microbial biotransformations are essential in the carbon cycle of ecosystems.
  9. Biocatalysts are employed in biotransformations for the production of fine chemicals.
  10. The study of biotransformations helps in unraveling complex metabolic pathways in living organisms.


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  • Updated 29/06/2024 - 14:35:59