Engrailed meaning

Engrailed means having a border or edge marked with a series of half-circles.


Engrailed definitions

Word backwards deliargne
Part of speech Engrailed is an adjective.
Syllabic division en-grailed
Plural The plural of the word "engrailed" is engrailed.
Total letters 9
Vogais (3) e,a,i
Consonants (5) n,g,r,l,d

Engrailed is a transcription factor protein that plays a critical role in development across various species. It is involved in regulating gene expression patterns that are essential for proper formation of the nervous system, as well as segmentation of the body during embryogenesis.

Structure and Function

The Engrailed protein contains a DNA-binding domain that allows it to interact with specific regions of DNA, thereby influencing the expression of target genes. It also has a repressor domain that helps in controlling the activation of these target genes.

Developmental Role

During embryonic development, Engrailed is responsible for establishing the boundaries between different segments of the body plan. This segmentation process is crucial for the correct positioning of various structures and organs in the developing organism.

Neurological Significance

In the nervous system, Engrailed is involved in the differentiation and specification of neurons, as well as in the patterning of neural circuits. Disruptions in Engrailed expression have been linked to neurodevelopmental disorders and defects in brain development.

Overall, Engrailed plays a multifaceted role in development, influencing both the physical structure of an organism and the intricate wiring of its nervous system. Its functions are tightly regulated to ensure proper growth and differentiation, making it a key player in the complex orchestra of developmental processes.


Engrailed Examples

  1. The engrailed pattern on the fabric was intricate and beautiful.
  2. The engrailed edge of the pie crust added a decorative touch to the dessert.
  3. The knight wore a shield with an engrailed border into battle.
  4. The engrailed design on the vintage silverware was unique and eye-catching.
  5. The engrailed border on the family crest represented strength and unity.
  6. The engrailed seams on the leather jacket gave it a rugged appearance.
  7. The engrailed hemline on the dress added flair and elegance to the outfit.
  8. The engrailed pattern on the tablecloth matched the curtains perfectly.
  9. The engrailed details on the antique chest were expertly crafted by hand.
  10. The engrailed border on the parchment scroll indicated importance and prestige.


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  • Updated 19/04/2024 - 11:44:43