Diapedeses meaning

The process of diapedesis refers to the movement of white blood cells from the bloodstream into tissues.


Diapedeses definitions

Word backwards sesedepaid
Part of speech The part of speech of the word "diapedeses" is a noun.
Syllabic division di-ap-e-des-es
Plural The plural of diapedesis is diapedeses.
Total letters 10
Vogais (3) i,a,e
Consonants (3) d,p,s

Diapedesis, also known as extravasation, is the process by which white blood cells migrate from the bloodstream to surrounding tissues. This critical step in the immune response allows white blood cells to reach sites of infection or injury where they are needed to combat pathogens and promote healing.

Process of Diapedesis

During diapedesis, white blood cells adhere to the walls of blood vessels and undergo a series of intricate steps to squeeze between the endothelial cells that line the blood vessel walls. This process involves the activation of adhesion molecules and cytoskeletal rearrangements that allow the white blood cells to cross the endothelial barrier and enter the tissue.

Importance of Diapedesis

Diapedesis is a crucial part of the body's immune response, as it enables white blood cells to quickly and efficiently reach areas of infection or inflammation. Without diapedesis, the ability of the immune system to combat pathogens and heal damaged tissues would be severely compromised.

Role of Inflammation

Inflammation is closely linked to diapedesis, as the process of white blood cells leaving the bloodstream and entering tissues is a key component of the inflammatory response. Inflammatory mediators released at the site of injury or infection trigger the upregulation of adhesion molecules, facilitating the movement of white blood cells from the bloodstream to the affected area.

Disorders Related to Diapedesis

Abnormalities in diapedesis can lead to various health conditions, including chronic inflammation, autoimmune diseases, and impaired wound healing. Understanding the mechanisms of diapedesis and investigating potential therapeutic targets is essential for developing treatments for these disorders.

White blood cells play a critical role in the immune system's response to infections and injuries, with diapedesis being a key mechanism that allows them to reach the site of action. By understanding the process of diapedesis and its importance in immune responses, researchers can develop new strategies to modulate this process for therapeutic purposes.

Adhesion molecules and cytoskeletal rearrangements are essential components of diapedesis, enabling white blood cells to adhere to blood vessel walls and migrate into tissues. Targeting these mechanisms may offer potential therapeutic interventions for conditions characterized by abnormal diapedesis, such as inflammatory diseases and cancer metastasis.


Diapedeses Examples

  1. The diapedeses of white blood cells through blood vessel walls is a crucial step in the immune response.
  2. Increased diapedeses can be a sign of inflammation in the body.
  3. Researchers are studying the molecular mechanisms behind diapedeses in order to develop new treatments.
  4. Understanding the process of diapedeses is important for diagnosing certain medical conditions.
  5. The movement of cells through diapedeses can be influenced by various factors.
  6. Some diseases can disrupt the normal process of diapedeses in the body.
  7. Doctors use diapedeses as a diagnostic tool to monitor certain health conditions.
  8. Disorders affecting diapedeses can have serious consequences for a person's health.
  9. Improving our understanding of diapedeses could lead to new advancements in medicine.
  10. Cell migration through diapedeses plays a key role in the body's defense against pathogens.


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  • Updated 09/07/2024 - 15:47:21