Androgen insensitivity syndrome meaning

Androgen insensitivity syndrome is a genetic condition where individuals with XY chromosomes have insensitivity to male sex hormones, resulting in various degrees of feminization despite having male genotype.


Androgen insensitivity syndrome definitions

Word backwards negordna ytivitisnesni emordnys
Part of speech Noun
Syllabic division an-dro-gen in-sen-si-tiv-i-ty syn-drome
Plural The plural of the word androgen insensitivity syndrome is androgen insensitivity syndromes.
Total letters 29
Vogais (4) a,o,e,i
Consonants (9) n,d,r,g,s,t,v,y,m

Androgen insensitivity syndrome, also known as AIS, is a genetic condition that affects sexual development before birth and during puberty. It occurs when a person with XY chromosomes, which typically develop as male, is partially or completely unable to respond to androgens, the hormones responsible for male sexual development. This can result in a range of physical characteristics, depending on the degree of insensitivity to androgens.

Symptoms of Androgen Insensitivity Syndrome

Individuals with AIS may have external female genitalia, even though they have XY chromosomes. They may also have undescended testes, which can increase the risk of developing testicular cancer. Additionally, individuals with AIS often have reduced body hair and a lack of menstruation.

Diagnosis and Treatment

AIS is typically diagnosed through genetic testing, which can identify mutations in the androgen receptor gene. Treatment for AIS typically involves hormone therapy to promote the development of secondary sexual characteristics. Some individuals may choose to undergo surgery to create a more typically female appearance of the external genitalia.

Psychosocial Impact

Living with AIS can have a significant psychosocial impact on individuals, as they may face challenges related to gender identity, body image, and fertility. It is essential for individuals with AIS to have access to appropriate support and resources to navigate these challenges and live fulfilling lives.

Androgen insensitivity syndrome is a complex genetic condition that requires a multidisciplinary approach to management, involving endocrinologists, genetic counselors, psychologists, and other healthcare providers. With the right support, individuals with AIS can lead healthy and fulfilling lives, navigating the challenges associated with their condition with resilience and grace.


Androgen insensitivity syndrome Examples

  1. Individuals with androgen insensitivity syndrome may have external female genitalia but internal male reproductive organs.
  2. The diagnosis of androgen insensitivity syndrome is often made through genetic testing.
  3. Treatment for androgen insensitivity syndrome may include hormone therapy.
  4. People with androgen insensitivity syndrome may have difficulty conceiving children naturally.
  5. Androgen insensitivity syndrome is a genetic condition that affects sexual development.
  6. Individuals with complete androgen insensitivity syndrome are typically raised as females.
  7. The prevalence of androgen insensitivity syndrome is estimated to be about 1 in 20,000 individuals.
  8. Androgen insensitivity syndrome can cause a range of physical and emotional challenges.
  9. People with androgen insensitivity syndrome may undergo surgeries to feminize external genitalia.
  10. The androgen receptor gene mutation is responsible for androgen insensitivity syndrome.


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  • Updated 09/05/2024 - 15:22:34